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Preschool Language Development of Children Born to Women with an Opioid Use Disorder
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In: Children (Basel) (2021)
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Abstract:
Increasing evidence suggests that prenatal exposure to opioids may affect brain development, but limited data exist on the effects of opioid-exposure on preschool language development. Our study aimed to characterize the nature and prevalence of language problems in children prenatally exposed to opioids, and the factors that support or hinder language acquisition. A sample of 100 children born to pregnant women in methadone maintenance treatment and 110 randomly identified non-exposed children were studied from birth to age 4.5 years. At 4.5 years, 89 opioid-exposed and 103 non-exposed children completed the preschool version of the Clinical Evaluation of Language Fundamentals (CELF-P) as part of a comprehensive neurodevelopmental assessment. Children prenatally exposed to opioids had poorer receptive and expressive language outcomes at age 4.5 years compared to non-opioid exposed children. After adjustment for child sex, maternal education, other pregnancy substance use, maternal pregnancy nutrition and prenatal depression, opioid exposure remained a significant independent predictor of children’s total CELF-P language score. Examination of a range of potential intervening factors showed that a composite measure of the quality of parenting and home environment at age 18 months and early childhood education participation at 4.5 years were important positive mediators.
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Keyword:
Article
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URL: https://doi.org/10.3390/children8040268 http://www.ncbi.nlm.nih.gov/pubmed/33807265 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066299/
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A Pilot Study of Early Storybook Reading With Babies With Hearing Loss
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Integrating health, education and culture in predicting Pacific children's English receptive vocabulary at 6 years: A classification tree approach
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International Survey of Speech-Language Pathologists⠐ractices in Working with Children with Autism Spectrum Disorder
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Promoting language and social communication development in babies through an early storybook reading intervention
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Content validity to support the use of a computer-based phonological awareness screening and monitoring assessment (Com-PASMA) in the classroom ...
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Content validity to support the use of a computer-based phonological awareness screening and monitoring assessment (Com-PASMA) in the classroom ...
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Content validity to support the use of a computer-based phonological awareness screening and monitoring assessment (Com-PASMA) in the classroom ...
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Content validity to support the use of a computer-based phonological awareness screening and monitoring assessment (Com-PASMA) in the classroom ...
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Assessing Language Production using SALT Software. A Clinician's Guide to Language Sample Analysis. New Zealand version
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Evaluating the clinical utility of the Profile of Oral Narrative Ablility in 4-year-old children
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Profiling oral narrative ability in young school-aged children
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